Structure of PDB 8d2z Chain B Binding Site BS01

Receptor Information
>8d2z Chain B (length=304) Species: 95486 (Burkholderia cenocepacia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVTWTKLSENAYAYTAEGDPNSGVIIGDDSVLIVDTTATPAMAQDLIAKI
RSVTDKPIKHVVLSHYHAVRVLGASAYFDEGAQHVIASRGTYEMIVERGE
ADMKSEIERFPRLFAGVETVPGLTWPTLVFEREITLFLGKLEVKIMHVGS
GHTKGDTIVWLPSQKVLFSGDLVEYDAACYCGDAQLEQWPATLEALRALG
AEKLVPGRGPALLNPAEVNKGLDYTKDFVTTLLAQGRKAVERNLDLKAAM
ALTREAMDPKFGHVFIYEHCLPFDVSRAFDEASGIAHPRIWTAQRDKDMW
AALQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8d2z Chain B Residue 400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8d2z Crystal Structure of a Metallo-beta-lactamase superfamily protein from Burkholderia cenocepacia
Resolution1.85 Å
Binding residue
(original residue number in PDB)		H79 H81 H166
Binding residue
(residue number reindexed from 1)		H65 H67 H152
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8d2z, PDBe:8d2z, PDBj:8d2z
PDBsum8d2z
PubMed
UniProtB4EIY5

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