Structure of PDB 8cv7 Chain B Binding Site BS01
Receptor Information
>8cv7 Chain B (length=109) Species:
9606
(Homo sapiens) [
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SSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMD
LSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDV
FEFRYAKMP
Ligand information
>8cv7 Chain C (length=12) Species:
32630
(synthetic construct) [
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WYGYWKVPKRKC
Receptor-Ligand Complex Structure
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PDB
8cv7
Peptide 2.2E in complex with BRD2-BD2
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
A367 W370 V376 L381 N429 H433 D434 V435 M438
Binding residue
(residue number reindexed from 1)
A22 W25 V31 L36 N84 H88 D89 V90 M93
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8cv7
,
PDBe:8cv7
,
PDBj:8cv7
PDBsum
8cv7
PubMed
37269828
UniProt
P25440
|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)
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