Structure of PDB 8cv4 Chain B Binding Site BS01
Receptor Information
>8cv4 Chain B (length=115) Species:
9606
(Homo sapiens) [
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KVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPM
DMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD
VFEMRFAKMPDEPEE
Ligand information
>8cv4 Chain C (length=12) Species:
32630
(synthetic construct) [
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WKYWRKYVLKIC
Receptor-Ligand Complex Structure
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PDB
8cv4
Peptide 4.2C in complex with BRD4.2
Resolution
1.93 Å
Binding residue
(original residue number in PDB)
W374 P375 F376 Y377 L385 L387 H437 E438 V439
Binding residue
(residue number reindexed from 1)
W26 P27 F28 Y29 L37 L39 H89 E90 V91
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8cv4
,
PDBe:8cv4
,
PDBj:8cv4
PDBsum
8cv4
PubMed
37269828
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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