Structure of PDB 8cp6 Chain B Binding Site BS01

Receptor Information
>8cp6 Chain B (length=1084) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVNPMLGSKLLPEEVDFALAAPDTFTFARGYLSSNPRIGRLGRGWWLPGE
SMHLELSEDACVLVDAQGRRIGFPALAPGAQHYSGSEELWLRRGGSSGGE
AQAWRGRWAAVPAELQTQEGSVLVLSGHSYLHFQRCPDGIWRLQASFGRA
GYRTEFRWSGRGLLTGVRDSAGRSYALVYQQACEPSEGDDGLRLFGVILA
SHDGPPPDYIDPQSPGLDWLVRYQFSDSGDLIAVRDRLGQVVRVFAWREH
MLVAHGEPGGLEVRYEWDVHAPHGRVVKQIEAGGLTRTFRYLRDATEVSD
SLGRVERYEFAGEGGQRRWTALVRADGSRSEFDYDLFGRLVAMRDPLGRE
TRRRRDGQGRMLEEESPGKARYRKRVDEETGLLVELEDAMQRRWTFERDE
RGNATTVRGPAGSTRYAYEDPRLPDRPTRIVDPRGGERRLEWNRFGLLAA
LTDCSGQVWRYDYDNEGRLVASSDPLGQLTRRRYDPLGQLIGLELADGSA
LSYEYDALGRQTRIADAEGHATLFSWGHGDLLARVSDAGGGELSYLHDEA
GRLVALTNENGVQAQFRYDLLDRLVEETGFDGRRQRYRYNAADELIARED
ADGRETTYAYDRDGRLASIRVPATEHAPALVERYRWLADGRLASAGGADC
EVRYTYDEVGNLRLESQVHADGWVYSVEHSHDALGVRQTSRYGDAPPVAW
LTYGPGHLHGALVGAVELAFERDALHREVRRDARRDGQDDALFTQERQHA
PLGRLQRSRLRLAGGFDWQRGYRYDGLGQLVGIDDNQYPSVRYEYDLGGR
LLASRRAGAAASTYRYDAAGNRLEGARWAGNRVERIAGNRYRFDALGNLV
ERIGADGERLRLAYDGAQRLVHLTRDYADGTRLEARYRYDALSRRIAKVV
LRDGVEQQVRFGWDGDRQCAEAFARELRTTVHEPGGFVPLLRLEQACEPD
PPELLQLRQAFAAEGQPLPAQCVPALGEARIAFFHTDHLGTPLQLSDERG
QLRWQGVPDDWRAVAPERQPGAQPIRFQGQYHDEESGLYYNRYRYYLPEA
GRYASQDPLGLGGGPNPYAYALNAPTLAYDPTGL
Ligand information
>8cp6 Chain A (length=18) Species: 287 (Pseudomonas aeruginosa) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SAVGLADRVSACVPLVGK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cp6 Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		P48 V49 N50 P51 M52 L53 L57 L79 Q114 G115 R116 R117 I118 G119 F120 S131 Y312 Q326 R334 Y355 R364 W366
Binding residue
(residue number reindexed from 1)		P1 V2 N3 P4 M5 L6 L10 L32 Q67 G68 R69 R70 I71 G72 F73 S84 Y265 Q279 R287 Y308 R317 W319
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8cp6, PDBe:8cp6, PDBj:8cp6
PDBsum8cp6
PubMed38016939
UniProtQ9I0F4|TSE5_PSEAE Toxin protein Tse5 (Gene Name=tse5)

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