Structure of PDB 8c01 Chain B Binding Site BS01

Receptor Information
>8c01 Chain B (length=201) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYVQVRQPIF
VAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLD
IINVLTDQNPIQVVVDAITNTGPREDTTRVARRQAVDVSPLRRVNQAIAL
LTIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELERVAKSN
R
Ligand information
>8c01 Chain 2 (length=1545) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaaauacagugaaacugcgaauggcucauuaa
aucaguuaucguuuauuugauaguuacaugguauaacugugguaauucua
gagcuaauacaugcuuaaaaucucgaagagauguauuuauuagauaaaaa
uugaugauucauaauaacuuuucgaaucgcauggccgcuggcgaugguuc
auucaaauuucugcccuaucaacuuucgaugguaggauaguggccuacca
ugguuucaacggguaacggggaauaaggguucgauuccggagagggagcc
ugagaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauuaccc
aauccuaauucagggagguagugacaauaaauaacgauacagguuguauu
ggaaugaguacaauguaaauaccuuaacgaggaacaauuggagggcaagu
cuggugccagcagccgcgguaauuccagcuccaauagcguauauuaaagu
uguugcaguuaaaaagcucguaguugaacuuugggcccgguuggccaacg
gggccuuuuuuacuuugaaaaaauuagaguguucaaagcaggcgugcucg
aauauauuagcauggaauaauagaauaggacguuugguucuauuuuuuuc
uaggaccaucguaaugauuaauagggacggucgggggcaucaguauucaa
uugucagaggugaaauucuuggauuuauugaagacuaacuacugcgaaag
cauuugccaaggacguuuucauuaaucaagaacgaaaguuaggggaucga
agaugaucagauaccgucguagucuuaaccauaaacuaugccgacuaggg
aucgggugguguuuuuaaugacccacucggcaccuuacgagaaaucaaag
ucuuuggguucuggggggaguauggucgcaaggcugaaacuuaaaggaau
ugacagggcaccaccaggaguggagccugcggcuuaauuuggaaacucac
cagguccacacaauaagauugacagauugagagcucuuucuugauuuugu
ggguggugggccgguugguggagugauuugucugcuuaauugcgauaacg
aacgaccuuaaccacuaauaguggugcuagcauuugcugguuccacuucu
uagagggacuaggaaggaggggucccuuagacguucugggccgcacgcgc
gcuacacugacggagccagcgagucuaaccuuggccgagaggucuuggua
aucuugugaaacuccgucgugcuggggauagagcauuguaauuauugcuc
uucaacgaggaauuccuaguaagcgcaagucaucagcuugcguugauuac
gucccugcccuguaccuaguaccgauugaauggcuuagugaggccucagg
aucugcuuagagucagagcggagaauuuggacaaacuuggucauuuagag
gaacuaagguuuccguaggugaaccugcggaaggaucauuaaaga
..<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<<.
<<<..<<....<<....<<.......>>...>>.>>......<<......
..<<<..<<..<<....<<<........<<......<<.<<.......>>
.>>......>>........<<<<<...>>>>><.<.<<<<<<......((
...........>>>>>>.>...>...<<<<..<<<.>>>.>>>>....>>
>...>>>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>
>>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.
.........>>>.>>.<.<<<..>>>.>...>>>>>>.........<<<.
...<<<.....>>>..>>>..>....>.>.....<<<<<<<<.>>>>>>>
>......<<..<...........>..>>.........<<<<<((....<.
<<<<.....<<..))>>.......>>>>>>>>>>..>>>>>>>>>>....
.....<<<[[.....<.<<...<<<.<<....<<<<<<.<<<<..>>>>.
>>>>>>...<<<<<.<<.......<<...<.......>..<<<..>>>..
..>>......>>.>>..>>>.........<<<..<<<<<<<<.....)).
>>>>>>>>.>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<
<.<...<<<..(...>>>......>.>>>>>>..>>.......<<....>
>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<..
.<<<<..)......>>>>...>>>>>>>>..........<<<.<<.<<<.
.<<<<<<<<.<<<......>>>>>>>>>>>..>>>...<<..]]>>...>
>.....>>>.>>>.<<<......<<<<....>>>>....>>>..)))).}
....<<<<<<..<<.<<<<<<..<<<.<<<<<<................<
<<<<.<..<<<<<.......<<.<<<........>>>.>>......>>>>
>......<<<<<.<<<.<<<<......>>...<<<......>>>...>>.
>>>..<<<<..<<.<<<..<<<<<.<<<<<<<..>>>>>>>.>>>>>...
>>>.>>..........>>>>>>>>>.......>.>>>>>...>>.>>>>.
>>>.....<<<<<<<......<<.....<<..<<<<....>>>>..>>..
..>>.......>>>>>>>......<....<<<<<<..........>>>>>
>....>.....>>>>>>....<<<<<<<<.......>>>>>>>>......
>>...>>>>>>.....<<<<.<<....<<<<<<<<.<<<..<.<<..<..
.<<<<<<<.......>>>>>>>...>..>>.>..>>>.>>>>>>>>...>
>.>>>>....<<<<<<<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c01 Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H72 A78 R81 K84 N95 L97 N100 G101 R102 N104 G105 K107 K109 R112 N169 R180 F184 R185 N186 I190
Binding residue
(residue number reindexed from 1)		H53 A59 R62 K65 N76 L78 N81 G82 R83 N85 G86 K88 K90 R93 N145 R156 F160 R161 N162 I166
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000054 ribosomal subunit export from nucleus
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006450 regulation of translational fidelity
GO:0030490 maturation of SSU-rRNA
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c01, PDBe:8c01, PDBj:8c01
PDBsum8c01
PubMed36996028
UniProtP26783|RS5_YEAST Small ribosomal subunit protein uS7 (Gene Name=RPS5)

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