Structure of PDB 8bwn Chain B Binding Site BS01

Receptor Information
>8bwn Chain B (length=104) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHA
VIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVES
CGCR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8bwn Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8bwn Molecular mechanism of BMP signal control by Twisted gastrulation.
Resolution2.57 Å
Binding residue
(original residue number in PDB)		G413 D416
Binding residue
(residue number reindexed from 1)		G16 D19
Annotation score4
External links
PDB RCSB:8bwn, PDBe:8bwn, PDBj:8bwn
PDBsum8bwn
PubMed38862520
UniProtP43026|GDF5_HUMAN Growth/differentiation factor 5 (Gene Name=GDF5)

[Back to BioLiP]