Structure of PDB 8bn5 Chain B Binding Site BS01

Receptor Information
>8bn5 Chain B (length=267) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGFKYEIYQ
APDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKRY
MDYSVGILIKKGTPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLE
QDSTFAELWRTISKNGGADNCVSSPSEGIRKAKKGNYAFLWDVAVVEYAA
LTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVL
KQKWWPHMGRCDLTSHA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8bn5 Chain B Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8bn5 Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with GABA
Resolution1.9 Å
Binding residue
(original residue number in PDB)		E527 V530 D531
Binding residue
(residue number reindexed from 1)		E91 V94 D95
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8bn5, PDBe:8bn5, PDBj:8bn5
PDBsum8bn5
PubMed38060673
UniProtQ9ULK0|GRID1_HUMAN Glutamate receptor ionotropic, delta-1 (Gene Name=GRID1)

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