Structure of PDB 8bbu Chain B Binding Site BS01

Receptor Information
>8bbu Chain B (length=119) Species: 6421 (Hirudo medicinalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QFTDSCLRCICKVEGCDSQIGKCGMDVGSLSCGPYQIKKPYWIDCGKPGG
GYESCTKNKACSETCVRAYMKRYGTFCTGGRTPTCQDYARIHNGGPRGCK
SSATVGYWNKVQKCLRGTH
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain8bbu Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8bbu Structural basis for inhibition of thrombolytic destabilase from medical leech by physiological sodium concentrations
Resolution1.1 Å
Binding residue
(original residue number in PDB)		E34 D46
Binding residue
(residue number reindexed from 1)		E14 D26
Annotation score3
Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0016787 hydrolase activity
Biological Process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium

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Molecular Function
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Biological Process
External links
PDB RCSB:8bbu, PDBe:8bbu, PDBj:8bbu
PDBsum8bbu
PubMed37095116
UniProtQ25091

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