Structure of PDB 8b9z Chain B Binding Site BS01

Receptor Information
>8b9z Chain B (length=182) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QQTLPVAEVAQNLPKKGYSPFGTKQSSVAEWSLARLDDLLNWGRKGSIWP
LTFGLACCAVEMMHIAAPRYDMDRYGVVFRASPRQADVIIVAGTLTNKMA
PALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVP
GCPPTAEALMYGVLQLQKKVKRMKTLQMWYRK
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8b9z Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8b9z Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
Resolution3.28 Å
Binding residue
(original residue number in PDB)		C96 C97 G159 C161 C191 P192
Binding residue
(residue number reindexed from 1)		C57 C58 G120 C122 C152 P153
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0048038 quinone binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:8b9z, PDBe:8b9z, PDBj:8b9z
PDBsum8b9z
PubMed36622099
UniProtQ9VXK7

[Back to BioLiP]