Structure of PDB 8b5b Chain B Binding Site BS01

Receptor Information
>8b5b Chain B (length=125) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8b5b Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family.
Resolution1.92 Å
Binding residue
(original residue number in PDB)		W81 V87 L92 L94 Y139 D145
Binding residue
(residue number reindexed from 1)		W40 V46 L51 L53 Y98 D104
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8b5b, PDBe:8b5b, PDBj:8b5b
PDBsum8b5b
PubMed36585954
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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