Structure of PDB 8a7j Chain B Binding Site BS01

Receptor Information
>8a7j Chain B (length=345) Species: 80249 (Phaedon cochleariae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFSKEESREFMAIFPDIVRDLTDAGRHTDIPEVTKRFAKVLQYNVPTGKK
TRGLSTVIAYKMLEKPENLTPENVRLAGILGWCVELLQASLLIMDDLMDR
SETRRGQPCWYRQENVGFLAINDCLHVESSLYSVLRKYFSHLPCYVPIIE
LFHDVNFKTNMGQSLDALCMKDGRPILSQFTMKRYSSIVKYKTSYYTFQL
PVSLGMYLADMYDPEQHRQAKTILMEIGEFFQIQDDFLDAFGDSQVTGKV
GTDIKEGKCSWLAVVALQRSNPAQRQIMEEHYGRPEPESTQIIKNLYIEL
GLPATFAVYEEESFNIIRTHIHQISKGLPHDLFFKIMKKIYKRDA
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain8a7j Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8a7j Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Resolution1.2 Å
Binding residue
(original residue number in PDB)		D179 D183
Binding residue
(residue number reindexed from 1)		D95 D99
Annotation score1
Enzymatic activity
Enzyme Commision number 2.5.1.1: dimethylallyltranstransferase.
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008299 isoprenoid biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8a7j, PDBe:8a7j, PDBj:8a7j
PDBsum8a7j
PubMed37308711
UniProtM1JS91

[Back to BioLiP]