Structure of PDB 8a5m Chain B Binding Site BS01

Receptor Information
>8a5m Chain B (length=168) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGF
SSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQY
WAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQE
RVFPLFSVCSTGTYLRIW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a5m TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
Resolution2.918 Å
Binding residue
(original residue number in PDB)
N42 T43 R44 A69 F85 Q95 S158 C160
Binding residue
(residue number reindexed from 1)
N41 T42 R43 A68 F84 Q94 S157 C159
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:8a5m, PDBe:8a5m, PDBj:8a5m
PDBsum8a5m
PubMed35893676
UniProtQ9C029|TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 (Gene Name=TRIM7)

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