Structure of PDB 8a0m Chain B Binding Site BS01

Receptor Information
>8a0m Chain B (length=964) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDKTWLFGSYAWQGNPKALFLYMLVNCKETHECWWVADNEESMKSIKKST
GLKNITFTDSEKAKELFPHADVYVTENFRESYPVYMNENIKVFNTWHGVG
LKHIELALGMNSVLAESIVRKYVRNYDIYKNNVLFLTTSQAMEDHFLEDM
AISKELIIRGKYPRNAVYGPNGIHTYDINTLLPKNKIYEAFNSIDSIFYD
LLDAGVISTKRKQYLMDYFFGFKSMESLIADVDNCQLQPKSLKELHTFDI
FDTLIRRSTLRPFSIFDYVRDKAKASGIKFPLALTENWINVRNRAEHDVR
DIMRKTTFERQSDKIEITLDDIYTRLQKNLLLTDEQTDFLKQAEIEAEIA
HVEPIQKRINYLFSLKAKGHDVAMASDMYLPEDVIYKMLDRADTRLREIP
LYLSSTIGYQKSTGKLYQHIFFDLDYQYSRWTHYGDNKHADGSVPRRLGI
QTAVHDIDDFIPFENAMVNAMDNYNRYPAYQLATKMHRYRTQLVQENGFG
NTLFETKYYNYAYVGASFVPYINWAIKDAIKRGYETIYFISRDGHFLKQI
ADKIIEIRGYNVKTKYIYGSRKAWRLPSFITKVDDETFWQFGNFVGMDSF
EDLVKASYLSESELLSLFPEFESLREIAENIRKIFKNSPAYHEKVLAIAA
EKRKMVRQYIQQEINPKEKFAFVEFWGRGYTQDTFGRLLNDAFGKEVKNP
FYYVRSFTDDMGTSVRHNFILAPQNFSFFEPIFAQTPYDSIPDYYEEKGR
IEPIINHRDRSVSDLISEGLLKFTEDYLALNTQDEDYFDAALSQFNYQYQ
LNTPNDQFICNVFSELKDEKPYAPALTLKQLESITSKQELDKLTQSIPIS
LSKSDVKVIDYYNKIQKNYNLPAYNSTPMRKAYAVNPLEQYVWSTQVPFR
VLSLKQNSFYLDVSFAETTKRKDIFLKELNEIDVIAVDWLKGGVPRLLTE
HGYITAHKDWVKKS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8a0m Chain B Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8a0m A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		D386 F388 D573
Binding residue
(residue number reindexed from 1)		D249 F251 D436
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0047355 CDP-glycerol glycerophosphotransferase activity
Biological Process
GO:0019350 teichoic acid biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8a0m, PDBe:8a0m, PDBj:8a0m
PDBsum8a0m
PubMed37277468
UniProtQ2ERG0

[Back to BioLiP]