Structure of PDB 8a0c Chain B Binding Site BS01

Receptor Information
>8a0c Chain B (length=1113) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDKTWLFGSYAWQGNPKALFLYMLVNCKETHECWWVADNEESMKSIKKST
GLKNITFTDSEKAKELFPHADVYVTENFRESYPVYMNENIKVFNTWHGVG
LKHIELALGMNSVLAESIVRKYVRNYDIYKNNVLFLTTSQAMEDHFLEDM
AISKELIIRGKYPRNAVYGPNGIHTYDINTLLPKNKSQYSQTILFCPTYR
IGAIQGVLNSLLPDFAKLEEVCRHKNQLFIVKVHPFMKKDNYFAEMSEKY
KDSEYILFWNDDYDIYEAFNSIDLAIIDYSSIFYDLLDAGVEKFIRYVPD
LDEYQNDLELIGDYADLTEGRIVKSFQQLLNCLDNANIKIISTKRKQYLM
DYFFGFKKENKSMESLIADVDNCQLQPKSLKELHTFDIFDTLIRRSTLRP
FSIFDYVRDKAKASGIKFPLALTENWINVRNRAEHDVRDIMRKTTFERQS
DKIEITLDDIYTRLQKNLLLTDEQTDFLKQAEIEAEIAHVEPIQKRINYL
FSLKAKGHDVAMASDMYLPEDVIYKMLDRADTRLREIPLYLSSTIGYQKS
TGKLYQHIFFDLDYQYSRWTHYGDNKHADGSVPRRLGIQTAVHDIDDFIP
FENAMVNAMDNYNRYPAYQLATKMHRYRTQLVQENGFGNTLFETKYYNYA
YVGASFVPYINWAIKDAIKRGYETIYFISRDGHFLKQIADKIIEIRGYNV
KTKYIYGSRKAWRLPSFITKVDDETFWQFGNFVGMDSFEDLVKASYLSES
ELLSLFPEFESLRHAKHLRGEIAENIRKIFKNSPAYHEKVLAIAAEKRKM
VRQYIQQEINPKEKFAFVEFWGRGYTQDTFGRLLNDAFGKEVKNPFYYVR
SFTDDMGTSVRHNFILAPQNFSFFEPIFAQTPYDSIPDYYEEKGRIEPII
NHRDRSVSDLISEGLLKFTEDYLALNTQDEDYFDAALSQFNYQYQLNTPN
DQFICNVFSELKDNIGVEKPYAPALTLKQLESITSKQELDKLTQSIPISL
SKSDVKVIDYYNKIQKNYNLPAYNSTPMRKAYAVNPLEQYVWSTQVPFRV
LSLKQNSFYLDVSFAETTKRKDIFLKELNEIDVIAVDWLKGGVPRLLTEH
GYITAHKDWVKKS
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain8a0c Chain B Residue 1203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a0c A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D386 F388 S513 D514 K548
Binding residue
(residue number reindexed from 1)		D387 F389 S514 D515 K549
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0047355 CDP-glycerol glycerophosphotransferase activity
Biological Process
GO:0019350 teichoic acid biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a0c, PDBe:8a0c, PDBj:8a0c
PDBsum8a0c
PubMed37277468
UniProtQ2ERG0

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