Structure of PDB 7zy4 Chain B Binding Site BS01

Receptor Information
>7zy4 Chain B (length=306) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQEAQQVDMWKKYIQWEKSNPLRTEDQTLITKRVMFAYEQCLLVLGHHPD
IWYEAAQYLEQSSKLLAEKGDMNNAKLFSDEAANIYERAISTLLKKNMLL
YFAYADYEESRMKYEKVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIK
SGRMIFKKAREDTRTRHHVYVTAALMEYYCSKDKSVAFKIFELGLKKYGD
IPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGSLPPEKSGEIWARFLAFE
SNIGDLASILKVEKRRFTAFKEEYEGKETALLVDRYKFMDLYPCSASELK
ALGYKD
Ligand information
Receptor-Ligand Complex Structure
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PDB7zy4 Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		R395 K399 R402 V428 K431 L435
Binding residue
(residue number reindexed from 1)		R153 K157 R160 V186 K189 L193
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006396 RNA processing
GO:0031124 mRNA 3'-end processing
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:7zy4, PDBe:7zy4, PDBj:7zy4
PDBsum7zy4
PubMed36073787
UniProtQ12996|CSTF3_HUMAN Cleavage stimulation factor subunit 3 (Gene Name=CSTF3)

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