Structure of PDB 7zrj Chain B Binding Site BS01

Receptor Information
>7zrj Chain B (length=675) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGA
MPGNALFSAAISGWLWITVLFANFAEALAEGRSKAQANSLKGVKKTAFAR
KLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESA
ITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMV
EGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVA
LLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLN
KTGTITLGNRQASEFIPAQGVDEKTLADAAQLASLADETPEGRSIVILAK
QRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEA
NGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERF
AQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQ
AEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTK
LIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNI
MCLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIY
GLGGLLVPFIGIKVIDLLLTVCGLV
Ligand information
>7zrj Chain D (length=27) Species: 562 (Escherichia coli) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MSAGVITGVLLVFLLLGYLVYALINAE
Receptor-Ligand Complex Structure
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PDB7zrj Inhibited KdpFABC transitions into an E1 off-cycle state.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		W31 P34 F37 I38 I223 I226 T229 I230 L233 L234
Binding residue
(residue number reindexed from 1)		W24 P27 F30 I31 I216 I219 T222 I223 L226 L227
Enzymatic activity
Enzyme Commision number 7.2.2.6: P-type K(+) transporter.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008556 P-type potassium transmembrane transporter activity
GO:0015662 P-type ion transporter activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031004 potassium ion-transporting ATPase complex
GO:1903103 potassium:proton antiporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zrj, PDBe:7zrj, PDBj:7zrj
PDBsum7zrj
PubMed36255052
UniProtP03960|KDPB_ECOLI Potassium-transporting ATPase ATP-binding subunit (Gene Name=kdpB)

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