Structure of PDB 7zri Chain B Binding Site BS01

Receptor Information
>7zri Chain B (length=676) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASG
AMPGNALFSAAISGWLWITVLFANFAEALAEGRSKAQANSLKGVKKTAFA
RKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDES
AITGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAM
VEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLV
ALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLL
NKTGTITLGNRQASEFIPAQGVDEKTLADAAQLASLADETPEGRSIVILA
KQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVE
ANGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKER
FAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQY
QAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPT
KLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALN
IMCLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWI
YGLGGLLVPFIGIKVIDLLLTVCGLV
Ligand information
>7zri Chain D (length=27) Species: 562 (Escherichia coli) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MSAGVITGVLLVFLLLGYLVYALINAE
Receptor-Ligand Complex Structure
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PDB7zri Inhibited KdpFABC transitions into an E1 off-cycle state.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		F37 I38 I226 I230 L233
Binding residue
(residue number reindexed from 1)		F31 I32 I220 I224 L227
Enzymatic activity
Enzyme Commision number 7.2.2.6: P-type K(+) transporter.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008556 P-type potassium transmembrane transporter activity
GO:0015662 P-type ion transporter activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031004 potassium ion-transporting ATPase complex
GO:1903103 potassium:proton antiporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zri, PDBe:7zri, PDBj:7zri
PDBsum7zri
PubMed36255052
UniProtP03960|KDPB_ECOLI Potassium-transporting ATPase ATP-binding subunit (Gene Name=kdpB)

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