Structure of PDB 7zrg Chain B Binding Site BS01

Receptor Information
>7zrg Chain B (length=674) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGAM
PGNALFSAAISGWLWITVLFANFAEALAEGRSKAQANSLKGVKKTAFARK
LREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAI
TGESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVE
GAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVAL
LVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDK
TGTITLGNRQASEFIPAQGVDEKTLADAAQLASLADETPEGRSIVILAKQ
RFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVEAN
GGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFA
QLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQA
EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKL
IEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIM
CLHSPDSAILSAVIFNALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYG
LGGLLVPFIGIKVIDLLLTVCGLV
Ligand information
>7zrg Chain D (length=27) Species: 562 (Escherichia coli) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MSAGVITGVLLVFLLLGYLVYALINAE
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7zrg Inhibited KdpFABC transitions into an E1 off-cycle state.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		W31 P34 F37 I38 I219 I226 I230 L233 L234 A237
Binding residue
(residue number reindexed from 1)		W23 P26 F29 I30 I211 I218 I222 L225 L226 A229
Enzymatic activity
Enzyme Commision number 7.2.2.6: P-type K(+) transporter.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008556 P-type potassium transmembrane transporter activity
GO:0015662 P-type ion transporter activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031004 potassium ion-transporting ATPase complex
GO:1903103 potassium:proton antiporter complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7zrg, PDBe:7zrg, PDBj:7zrg
PDBsum7zrg
PubMed36255052
UniProtP03960|KDPB_ECOLI Potassium-transporting ATPase ATP-binding subunit (Gene Name=kdpB)

[Back to BioLiP]