Structure of PDB 7z8n Chain B Binding Site BS01

Receptor Information

>7z8n Chain B (length=292) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SNELDELASGINRMAETLQSAQEEMQHNIDQATEDVRQNLETIEIQNIEL
DLARKEALEASRIKSEFLANMSHEIRTPLNGILGFTNLLQKSELSPRQQD
YLTTIQKSAESLLGIINEILDFSKIEAGKLVLENLPFNLRDLIQDALTML
APAAHEKQLELVSLVYRDTPIQLQGDPQRLKQILTNLVGNAIKFTQGGTV
AVRAMLEDESDDRAQLRISVQDTGIGLSEEDQQALFKAFSQADNSLSRQA
GGTGLGLVISKRLIEQMGGEIGVDSTPGEGAEFWISLSLPKS

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

7z8n Chain B Residue 605 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7z8n Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS.
Resolution	2.64 Å
Binding residue (original residue number in PDB)	S495 T496
Binding residue (residue number reindexed from 1)	S275 T276
Annotation score	4

Enzymatic activity

Enzyme Commision number

2.7.13.3: histidine kinase.

Gene Ontology

	Molecular Function
GO:0000155	phosphorelay sensor kinase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

	Biological Process
GO:0007165	signal transduction
GO:0016310	phosphorylation

	Cellular Component
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:7z8n, PDBe:7z8n, PDBj:7z8n
PDBsum	7z8n
PubMed	35767996
UniProt	G3XD98

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