Structure of PDB 7z50 Chain B Binding Site BS01

Receptor Information
>7z50 Chain B (length=177) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RHFVHQFKGECYFTNGTQRIRLVTRYIYNREEYLRFDSDVGEYRAVTELG
RHSAEYYNKQYLERTRAELDTACRHNYEETEVPTSLRRLEQPNVAISLSN
TLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEM
TPHQGEVYTCHVEHPSLKSPITVEWRA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7z50 Structural plasticity in I-A g7 links autoreactivity to hybrid insulin peptides in type I diabetes.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		F11 G13 Y30 S57 Y60 Y61 Y65 R68 E72 H79 N80 E83 T84
Binding residue
(residue number reindexed from 1)		F7 G9 Y26 S53 Y56 Y57 Y61 R64 E68 H75 N76 E79 T80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7z50, PDBe:7z50, PDBj:7z50
PDBsum7z50
PubMed35967292
UniProtQ31135

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