Structure of PDB 7z1m Chain B Binding Site BS01

Receptor Information
>7z1m Chain B (length=1101) Species: 580240 (Saccharomyces cerevisiae W303) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INTAQDKWHLLPAFLKVKGLVKQHLDSFNYFVDTDLKKIIKANQLILSDV
DPEFYLKYVDIRVGKKSSSSTKDYLTPPHECRLRDMTYSAPIYVDIEYTR
GRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLDPGGYFIV
NGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKN
GKIYLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNL
EESSKLDIYTQQQALEYIGAKVKTMRRQKLTILQEGIEAIATTVIAHLTV
EALDFREKALYIAMMTRRVVMAMYNPKMIDDRDYVGNKRLELAGQLISLL
FEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALLSINVHSNNITSGLNRAI
STGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKSRKVSGPR
ALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLG
VEDITLIDSASLHLNYGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEF
ISIYSNSHQMAVHIATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDF
DDFLKLGLVEYLDVNEENDSYIALYEKDIVPSMTHLEIEPFTILGAVAGL
IPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKRIDTLLYLMTYPQQPMVK
TKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDRGFGRCET
RRKTTTVLKRYANHTQDIIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQ
SGQIYINKSVPTNSQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKV
LLRQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHG
FPSRMTVGKMIELISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNY
SGKDMLYSGITGECLQAYIFFGPIYYQKLKHMVLDKMHARARGPRAVLTR
QPTEGRSRDGGLRLGEMERDCVIAYGASQLLLERLMISSDAFEVDVCDKC
GLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPRLRLEDIFQ
Q
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7z1m Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		H456 E504 Q708 K911 K919 H1029
Binding residue
(residue number reindexed from 1)		H419 E467 Q671 K863 K871 H981
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation at RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0042797 tRNA transcription by RNA polymerase III
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7z1m, PDBe:7z1m, PDBj:7z1m
PDBsum7z1m
PubMed36070694
UniProtP22276|RPC2_YEAST DNA-directed RNA polymerase III subunit RPC2 (Gene Name=RET1)

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