Structure of PDB 7z1l Chain B Binding Site BS01

Receptor Information
>7z1l Chain B (length=1101) Species: 580240 (Saccharomyces cerevisiae W303) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INTAQDKWHLLPAFLKVKGLVKQHLDSFNYFVDTDLKKIIKANQLILSDV
DPEFYLKYVDIRVGKKSSSSTKDYLTPPHECRLRDMTYSAPIYVDIEYTR
GRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLDPGGYFIV
NGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKN
GKIYLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNL
EESSKLDIYTQQQALEYIGAKVKTMRRQKLTILQEGIEAIATTVIAHLTV
EALDFREKALYIAMMTRRVVMAMYNPKMIDDRDYVGNKRLELAGQLISLL
FEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALLSINVHSNNITSGLNRAI
STGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKSRKVSGPR
ALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLG
VEDITLIDSASLHLNYGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEF
ISIYSNSHQMAVHIATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDF
DDFLKLGLVEYLDVNEENDSYIALYEKDIVPSMTHLEIEPFTILGAVAGL
IPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKRIDTLLYLMTYPQQPMVK
TKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDRGFGRCET
RRKTTTVLKRYANHTQDIIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQ
SGQIYINKSVPTNSQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKV
LLRQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHG
FPSRMTVGKMIELISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNY
SGKDMLYSGITGECLQAYIFFGPIYYQKLKHMVLDKMHARARGPRAVLTR
QPTEGRSRDGGLRLGEMERDCVIAYGASQLLLERLMISSDAFEVDVCDKC
GLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPRLRLEDIFQ
Q
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7z1l Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		H456 Q708 K911 K919 H1029
Binding residue
(residue number reindexed from 1)		H419 Q671 K863 K871 H981
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation at RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0042797 tRNA transcription by RNA polymerase III
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7z1l, PDBe:7z1l, PDBj:7z1l
PDBsum7z1l
PubMed36070694
UniProtP22276|RPC2_YEAST DNA-directed RNA polymerase III subunit RPC2 (Gene Name=RET1)

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