Structure of PDB 7yxk Chain B Binding Site BS01

Receptor Information
>7yxk Chain B (length=308) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSEVERALDVLLQEAEELCIGSSVVELDRIPTALEFCREFYSKNQPVVIR
KALNWPAIGKWTPKYLIEALGDRSVDVAITPNGYADGLATQNGQEYFVLP
LETKMKLSEVVRRLDDPTGAVHYIQKQNSDLPELAADLRVSDLDFAQQSF
NKPPDAVNFWLGDERAVTSMHKDPYENVYCVISGHKDFVLIPPHQLSCVP
RGIYPTGVYKTSDSGQFYIEPLRDEEGSDQFTEWVSVDPLSPDLAKYPEY
ARAKPLKVRVHAGDILYLPNYWFHHVSQSHKCIAVNFWYDLDYDSRYCYY
RMLEQMTS
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7yxk Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7yxk Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans.
Resolution2.43 Å
Binding residue
(original residue number in PDB)		H175 D177 H278
Binding residue
(residue number reindexed from 1)		H171 D173 H274
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.-
3.1.1.4: phospholipase A2.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0106155 peptidyl-lysine 3-dioxygenase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7yxk, PDBe:7yxk, PDBj:7yxk
PDBsum7yxk
PubMed35410347
UniProtQ9VU77

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