Structure of PDB 7yx8 Chain B Binding Site BS01

Receptor Information
>7yx8 Chain B (length=438) Species: 239935 (Akkermansia muciniphila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGPDYLYAEYRALPSPRQTGKNLRIGDGFSKYDNMTGVYLEKGRHVVLVG
KTEGQEISLLLPNLMRKPAEGVQPTKDPNGWGLHKKQIPLKEGINIIDVE
TPANAYISYFTEDAGKAPKIPVHFVTGKANGYFDTTRGDTNKDWVRLLDQ
AVSPIMDARGKYIQVAYPVEFLKKFTKDRGTELINAYDKLIGIQYQLMGL
DKYGKIPENRVLARVNFNYYMFRDGDGVAYLGNDGTMRMVTDPENVLKGD
ACWGFSHAVGHVMQMRPMTWGGMTEVSNNIFSLQAAAKTGNESRLKRQGS
YDKARKEIIEGEIAYLQSKDVFNKLVPLWQLHLYFTKNGHPDFYPDVMEY
LRNNAGNYGGNDTVKYQFEFVKACCDVTKTDLTDFFEKWGFFKPGKFHIG
DYAQYDFNVTPEMVEETKKWIAGKGYPKPETDITELSE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7yx8 Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		Y287 F290 R291 D292 H325 H329 T342 E343 Y470
Binding residue
(residue number reindexed from 1)		Y219 F222 R223 D224 H257 H261 T274 E275 Y402
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7yx8, PDBe:7yx8, PDBj:7yx8
PDBsum7yx8
PubMed35882872
UniProtB2UPI7

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