Structure of PDB 7ykw Chain B Binding Site BS01

Receptor Information
>7ykw Chain B (length=37) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
Ligand information
>7ykw Chain A (length=27) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RLANFLVHSSNNFGAILSSTNVGSNTY
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7ykw A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core
Resolution3.6 Å
Binding residue
(original residue number in PDB)
N14 L16 S20 I26 S28 T30 V32
Binding residue
(residue number reindexed from 1)
N14 L16 S20 I26 S28 T30 V32
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:7ykw, PDBe:7ykw, PDBj:7ykw
PDBsum7ykw
PubMed36567711
UniProtP10997|IAPP_HUMAN Islet amyloid polypeptide (Gene Name=IAPP)

[Back to BioLiP]