Structure of PDB 7yjq Chain B Binding Site BS01

Receptor Information
>7yjq Chain B (length=323) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAK
IDGVTNFSNVTSCGTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDR
LGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVG
MLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVCEGNE
LAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGE
SLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAI
TPTLLKLFDVTADKVKDRTAFIR
Ligand information
Ligand IDAU
InChIInChI=1S/Au/q+1
InChIKeyZBKIUFWVEIBQRT-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Au+]
FormulaAu
NameGOLD ION
ChEMBL
DrugBankDB14534
ZINC
PDB chain7yjq Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7yjq Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		E246 T285 D465 H466
Binding residue
(residue number reindexed from 1)		E28 T67 D247 H248
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.-.-
Gene Ontology
Molecular Function
GO:0016772 transferase activity, transferring phosphorus-containing groups

View graph for
Molecular Function
External links
PDB RCSB:7yjq, PDBe:7yjq, PDBj:7yjq
PDBsum7yjq
PubMed36662362
UniProtA0A0R6L508|MCR1_ECOLX Probable phosphatidylethanolamine transferase Mcr-1 (Gene Name=mcr1)

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