Structure of PDB 7xz0 Chain B Binding Site BS01

Receptor Information
>7xz0 Chain B (length=386) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HCEEHLDPLSIYCEQDRTLVCGVCASLGSHRGHRLLPAAEAQARLKTQLP
QQKMQLQEASMRKEKTVAVLEHQLVEVEETVRQFRGAVGEQLGKMRMFLA
ALESSLDREAERVRGDAGVALRRELSSLNSYLEQLRQMEKVLEEVADKPQ
TEFLMKFSLVTSRLQKILSESPPPARLDIQLPVISDDFKFQVWKHMFRHL
MPALEELTFDPSSAHPSLVVSSSGRRVECSDQKAPPAGEDTRQFDKAVAV
VAQQLLSQGEHYWEVEVGDKPRWALGVMAADASRRGRLHAVPSQGLWLLG
LRDGKILEAHVEAKEPRALRTPERPPARIGLYLSFADGVLAFYDASNPDV
LTPIFSFHERLPGPVYPIFDVCWHDKGKNAQPLLLV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7xz0 Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xz0 Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane.
Resolution3.28 Å
Binding residue
(original residue number in PDB)		H89 C105 C108
Binding residue
(residue number reindexed from 1)		H5 C21 C24
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7xz0, PDBe:7xz0, PDBj:7xz0
PDBsum7xz0
PubMed37770719
UniProtQ1XH17|TRI72_MOUSE Tripartite motif-containing protein 72 (Gene Name=Trim72)

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