Structure of PDB 7xt4 Chain B Binding Site BS01

Receptor Information
>7xt4 Chain B (length=1263) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DMNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAG
KSFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSF
LRKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFS
NFDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGT
YTGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKSEDHNDELRKQAE
VIVEAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHH
LWDIKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVS
TRFRILGDTEYYSKDSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPFYF
GVQQPSDSIPGKEHTSFNILLDKENRYRIPRSALRGALRRDLRTAFGSGC
NVSLGGQILCNCKVCIEMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVE
DGSLFDIEVGPEGLTFPFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWL
GGLDSTGKGRFALKDIKIFEWDLNQKINEYIKERGMRGKEKELLEMGESS
LPDGLIPYKFFEERECLFPYKENLKPQWSEVQYTIEVGSPLLTADTISAL
TEPGNRDAIAYKKRVYNDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGD
LGKEDHEDCTCDMCIIFGNEHESSKIRFEDLELINGNEFEKLEKHIDHVA
IDRFTGGALDKAKFDTYPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTA
LSDIRDGLYPLGSKGGVGYGWVAGISIDDNVPDDFKEMINKTGPINNDYV
HPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDIITHEEFTEELLSGKI
NCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKFFNINGELMIPGSELR
GMLRTHFEALTKSCFAIFGEDSTKTLGGKLDKALHPCTGLSDGLCPGCHL
FGTTDYKGRVKFGFAKYENGPEWLITRGNNPERSLTLGVLESPRPAFSIP
DDESEIPGRKFYLHHNGWRIIRQKQLEIRETVQPERNVTTEVMDKGNVFS
FDVRFENLREWELGLLLQSLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHT
FKIDKIKRVPQSDIREYINKGYQKLIEWSGNNVLPQWHVIPHIDKLYKLL
WVPFLNDSKLEPDVRYPVLNEESKGYIEGSDYTYKKLGDKDNLPYKTRVK
GLTTPWSPWNPFQ
Ligand information
>7xt4 Chain a (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggcagaaaauuggguaccg
.....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xt4 Target RNA activates the protease activity of Craspase to confer antiviral defense.
Resolution3.08 Å
Binding residue
(original residue number in PDB)		R180 A188 K189 D190 R294 K320 R323 H328 Y367 K371 R380 R382 T387 Y389 F458 N492 S494 L495 G496 D542 G543 L545 F546 D698 E761 K802 K804 F805 S1461 R1505
Binding residue
(residue number reindexed from 1)		R176 A184 K185 D186 R266 K292 R295 H300 Y339 K343 R352 R354 T359 Y361 F417 N451 S453 L454 G455 D501 G502 L504 F505 D657 E720 K761 K763 F764 S1042 R1086
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7xt4, PDBe:7xt4, PDBj:7xt4
PDBsum7xt4
PubMed36306795
UniProtA0A0B0EGF3

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