Structure of PDB 7xss Chain B Binding Site BS01

Receptor Information
>7xss Chain B (length=1282) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DMNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAG
KSFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSF
LRKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFS
NFDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGT
YTGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKSEDHNDELRKQAE
VIVEAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHH
LWDIKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVS
TRFRILGDTEYYSKDSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPFYF
GVQQPSDSIPGKEKKSEDSLVINEHTSFNILLDKENRYRIPRSALRGALR
RDLRTAFGSGCNVSLGGQILCNCKVCIEMRRITLKDSVSDFSEPPEIRYR
IAKNPGTATVEDGSLFDIEVGPEGLTFPFVLRYRGHKFPEQLSSVIRYWE
ENDGKNGMAWLGGLDSTGKGRFALKDIKIFEWDLNQKINEYIKERGMRGK
EKELLEMGESSLPDGLIPYKFFEERECLFPYKENLKPQWSEVQYTIEVGS
PLLTADTISALTEPGNRDAIAYKKRVYNDGNNAIEPEPRFAVKSETHRGI
FRTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHESSKIRFEDLELINGNEF
EKLEKHIDHVAIDRFTGGALDKAKFDTYPLAGSPKKPLKLKGRFWIKKGF
SGDHKLLITTALSDIRDGLYPLGSKGGVGYGWVAGISIDDNVPDDFKEMI
NGPINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDIITHEEF
TEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKFFNINGE
LMIPGSELRGMLRTHFEALTKSCFAIFGEDSTKTLGGKLDKALHPCTGLS
DGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLITRGNNPERSLTLGVLE
SPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQLEIRETVQPERNVTTE
VMDKGNVFSFDVRFENLREWELGLLLQSLDPGKNIAHKLGKGKPYGFGSV
KIKIDSLHTFKINSNNDKIKRVPQSDIREYINKGYQKLIEWSGNNSIQKG
NVLPQWHVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEESKGYIEGSD
YTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQ
Ligand information
>7xss Chain A (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggcagaaaauuggacgau
....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xss Target RNA activates the protease activity of Craspase to confer antiviral defense.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K187 K292 R294 K320 R323 Y367 K371 R382 D542 G543 S544 L545 F546 D749 E761 H762 D801 K802 K804 F805 T1423 L1459 E1460 S1461 R1505 L1648
Binding residue
(residue number reindexed from 1)		K183 K264 R266 K292 R295 Y339 K343 R354 D512 G513 S514 L515 F516 D719 E731 H732 D771 K772 K774 F775 T1013 L1049 E1050 S1051 R1095 L1238
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7xss, PDBe:7xss, PDBj:7xss
PDBsum7xss
PubMed36306795
UniProtA0A0B0EGF3

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