Structure of PDB 7xsr Chain B Binding Site BS01

Receptor Information
>7xsr Chain B (length=1287) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DMNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAG
KSFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSF
LRKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFS
NFDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGT
YTGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKSEDHNDELRKQAE
VIVEAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHH
LWDIKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVS
TRFRILGDTEYYSKAHDSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPF
YFGVQQPSDSIPGKEKKSEDSLVINEHTSFNILLDKENRYRIPRSALRGA
LRRDLRTAFGSGCNVSLGGQILCNCKVCIEMRRITLKDSVSDFSEPPEIR
YRIAKNPGTATVEDGSLFDIEVGPEGLTFPFVLRYRGHKFPEQLSSVIRY
WEENDGKNGMAWLGGLDSTGKGRFALKDIKIFEWDLNQKINEYIKERGMR
GKEKELLEMGESSLPDGLIPYKFFEERECLFPYKENLKPQWSEVQYTIEV
GSPLLTADTISALTEPGNRDAIAYKKRVYNDGNNAIEPEPRFAVKSETHR
GIFRTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHESSKIRFEDLELINGN
EFEKLEKHIDHVAIDRFTGGALDKAKFDTYPLAGSPKKPLKLKGRFWIKK
GFSGDHKLLITTALSDIRDGLYPLGSKGGVGYGWVAGISIDDNVPDDFKE
MINKTEGPINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDII
THEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKFF
NINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTKTLGGKLDKALHP
CTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLITRGNNPERSLT
LGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQLEIRETVQPER
NVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKNIAHKLGKGKPY
GFGSVKIKIDSLHTFKINSNNDKIKRVPQSDIREYINKGYQKLIEWSGNN
SIQKGNVLPQWHVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEESKGY
IEGSDYTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xsr Target RNA activates the protease activity of Craspase to confer antiviral defense.
Resolution2.97 Å
Binding residue
(original residue number in PDB)		K292 R294 K320 R323 H328 Y367 K371 R382 F458 D542 G543 L545 D698 E761 K802 F805 E1460 R1505 L1648
Binding residue
(residue number reindexed from 1)		K264 R266 K292 R295 H300 Y339 K343 R354 F430 D514 G515 L517 D670 E733 K774 F777 E1055 R1100 L1243
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7xsr, PDBe:7xsr, PDBj:7xsr
PDBsum7xsr
PubMed36306795
UniProtA0A0B0EGF3

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