Structure of PDB 7xsp Chain B Binding Site BS01

Receptor Information
>7xsp Chain B (length=1271) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DMNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAG
KSFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSF
LRKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFS
NFDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGT
YTGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKSEDHNDELRKQAE
VIVEAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHH
LWDIKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVS
TEYYSKSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPFYFGVQQPSDSI
PGKEKKEHTSFNILLDKENRYRIPRSALRGALRRDLRTAFGSGCNVSLGG
QILCNCKVCIEMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFD
IEVGPEGLTFPFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDST
GKGRFALKDIKIFEWDLNQKINEYIKERGMRGKEKELLEMGESSLPDGLI
PYKFFEERECLFPYKENLKPQWSEVQYTIEVGSPLLTADTISALTEPGNR
DAIAYKKRVYNDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDH
EDCTCDMCIIFGNEHESSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTG
GALDKAKFDTYPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRD
GLYPLGSKGGVGYGWVAGISIDDNVPDDFKEMINGPINNDYVHPGHQSPK
QDHKNKNIYYPHYFLDSGSKVYREKDIITHEEFTEELLSGKINCKLETLT
PLIIPDTSDENGLKLQGNKPGHKNYKFFNINGELMIPGSELRGMLRTHFE
ALTKSCFAIFGEDSTLSWCASKTLGGKLDKALHPCTGLSDGLCPGCHLFG
TTDYKGRVKFGFAKYENGPEWLITRGNNPERSLTLGVLESPRPAFSIPDD
ESEIPGRKFYLHHNGWRIIRQKQLEIRETVQPERNVTTEVMDKGNVFSFD
VRFENLREWELGLLLQSLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHTFK
INSNNDKIKRVPQSDIREYINKGYQKLIEWSGNNSIQKGNVLPQWHVIPH
IDKLYKLLWVPFLNDSKLEPDVRYPVLNEESKGYIEGSDYTYKKLGDKDN
LPYKTRVKGLTTPWSPWNPFQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xsp Target RNA activates the protease activity of Craspase to confer antiviral defense.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		R294 I295 R323 Y367 K371 F458 D542 G543 L545 F546 D698 D801 K802 K804 F805 E1460 S1461 R1505 L1648
Binding residue
(residue number reindexed from 1)		R266 I267 R295 Y339 K343 F411 D495 G496 L498 F499 D651 D754 K755 K757 F758 E1039 S1040 R1084 L1227
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7xsp, PDBe:7xsp, PDBj:7xsp
PDBsum7xsp
PubMed36306795
UniProtA0A0B0EGF3

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