Structure of PDB 7xpx Chain B Binding Site BS01

Receptor Information
>7xpx Chain B (length=86) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVI
RDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>7xpx Chain I (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcacaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacggaatccgtacgtgcgtttaagcggtgctag
agctgtctacgaccaattgagcggcctcggcaccgggattgtgat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7xpx Structural basis of nucleosomal H4K20 methylation by methyltransferase SET8.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		R45 I46 G48 R78 K79 T80
Binding residue
(residue number reindexed from 1)		R29 I30 G32 R62 K63 T64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7xpx, PDBe:7xpx, PDBj:7xpx
PDBsum7xpx
PubMed35532550
UniProtP62799|H4_XENLA Histone H4

[Back to BioLiP]