Structure of PDB 7xi3 Chain B Binding Site BS01

Receptor Information

>7xi3 Chain B (length=314) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RSTKGASKARRDQINAEIRNLKELLPLAEADKVRLSYLHIMSLACIYTRK
GVFFAGGTPLAGPTGLLSAQELEDIVAALPGFLLVFTAEGKLLYLSESVS
EHLGHSMVDLVAQGDSIYDIIDPADHLTVRQQLTMLDADRLFRCRFNTSK
SLRRQSSGNKLVLIRGRFHAHPPGAYWAGNPVFTAFCAPLEPLFLAMFQS
RHAKDLALLDVSESVLIYLGFERSELLCKSWYGLLHPEDLAQASSQHYRL
LAESGDIQAEMVVRLQAKHGGWTWIYCMLYSEGPEGPITANNYPISDTEA
WSLRQQLNSEDTQA

Ligand information

>7xi3 Chain D (length=16) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ccatcactcacgacct

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7xi3 Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.
Resolution	4.274 Å
Binding residue (original residue number in PDB)	T5 K6 K10 R13 S38 Y39
Binding residue (residue number reindexed from 1)	T3 K4 K8 R11 S36 Y37

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0046983	protein dimerization activity

View graph for
Molecular Function

External links

PDB	RCSB:7xi3, PDBe:7xi3, PDBj:7xi3
PDBsum	7xi3
PubMed	36343253
UniProt	Q8BGD7\|NPAS4_MOUSE Neuronal PAS domain-containing protein 4 (Gene Name=Npas4)

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