Structure of PDB 7xeb Chain B Binding Site BS01

Receptor Information
>7xeb Chain B (length=533) Species: 673 (Grimontia hollisae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EQCDLSQFQTTSSNQLMAAIRQQGASCVNALFSADTGVQEAAFSSNHMYN
VAQYTRTLAQQYAGGGSDELEALYLYLRAGYYAEFYNSNITFLSWVTPAV
KGAVDAFVQNAHFYDNGDAHGKVLNEVIITMDSAGLQHAYLDVVTQWLTR
WNAQYAEHWYMRNAVNGVFTLLFGGQWNNQYTSLIGEQTALVTALQAFAL
DRTKVNSPTEFMAANAARELGRLARYTDATIAPKVTEGLTAIFGQYPSYG
DGDAIWLGAADTASYYADCSQFNICGFEDALRDAALNQTFICSDTIKIRS
QDMSQAQHLAACDKMAYEESFFHTTLETGNQPVADDHNTQLQVNIFNSDT
DYGKYAGPIFGIDTNNGGMYLEGNPANVGNIPNFIAYEASYANPDHFVWN
LEHEYVHYLDGRFNMYGDFGTPTELVVWWSEGVAEYVSRVNDNPQAIATI
QDGSTYTLAQVFDTTYDGFDVDRIYRWGYLAVRFMFERHPDEVQRMLSAT
RQGRWAEYKAIISGWANQYQSEFAQWTEALAKG
Ligand information
Receptor-Ligand Complex Structure
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PDB7xeb Crystal structure of Grimontia hollisae collagenase provides insights into its novel substrate specificity toward collagen.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		G457 M458 Y459 E493 H496 F508 E520 Y555 F558 Y564
Binding residue
(residue number reindexed from 1)		G368 M369 Y370 E404 H407 F419 E431 Y466 F469 Y475
Enzymatic activity
Enzyme Commision number 3.4.24.3: microbial collagenase.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xeb, PDBe:7xeb, PDBj:7xeb
PDBsum7xeb
PubMed35679897
UniProtF7IZI6

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