Structure of PDB 7wku Chain B Binding Site BS01
Receptor Information
>7wku Chain B (length=299) Species:
1586324
(Porcine deltacoronavirus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SAGIKILLHPSGVVERCMVSVVYNGSALNGIWLKNVVYCPRHVIGKFRGD
QWTHMVSIADCRDFIVKCPIQGIQLNVQSVKMVGALLQLTVHTNNTATPD
YKFERLQPGSSMTIACAYDGIVRHVYHVVLQLNNLIYASFLNGACGSVGY
TLKGKTLYLHYMHHIEFNNKTHSGTDLEGNFYGPYVDEEVIQQQTAFQYY
TDNVVAQLYAHLLTVDARPKWLAQSQISIEDFNSWAANNSFANFPCEQTN
MSYIMGLSQTARVPVERILNTIIQLTTNRDSYDFECDWTPEMVYNQAPI
Ligand information
>7wku Chain K (length=5) Species:
32630
(synthetic construct) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
gAVLa
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7wku
The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
H41 K45 F139 G142 C144 H162 H163 I164 E165 F166 E188
Binding residue
(residue number reindexed from 1)
H42 K46 F140 G143 C145 H163 H164 I165 E166 F167 E189
Enzymatic activity
Enzyme Commision number
2.1.1.57
: methyltransferase cap1.
3.4.19.12
: ubiquitinyl hydrolase 1.
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
Gene Ontology
Molecular Function
GO:0008233
peptidase activity
Biological Process
GO:0019082
viral protein processing
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:7wku
,
PDBe:7wku
,
PDBj:7wku
PDBsum
7wku
PubMed
35336895
UniProt
A0A140ESF0
[
Back to BioLiP
]