Structure of PDB 7wi1 Chain B Binding Site BS01

Receptor Information

>7wi1 Chain B (length=372) Species: 77133 (uncultured bacterium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AGGKVTSSTGIAPKRYVYYPGSEELGPDEIRVIACGTGMPTARRAQAAAA
WVVELGNGDKFIVDIGSGSMANIQSLMIPANYLTKIFLTHLATDHWGDLV
SMWAGGWTAGRTDPLEVWGPSGSREDMGTKYAVEHMLKAYNWDYMTRAVT
INPRPGDINVHEFDYRALNEVVYQENGVTFRSWPCIHAGDGPVSFALEWN
GYKVVFGGDTAPNIWYPEYAKGADLAIHECWMTSDQMMTKYNQPAQLALR
INLDFHTSAQSFGQIMNMVQPRHAVAYHFFNDDDTRYDIYTGVRENYAGP
LSMATDMMVWNITRDAVTERMAVSPDHAWDVAGPSEDLAPDRNRASEYTQ
YILDGRLNVDEANAHWKQEFMG

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

7wi1 Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	7wi1 Structural study of metal binding and coordination of ancient metallo beta lactamase PNGM 1 variants
Resolution	1.61 Å
Binding residue (original residue number in PDB)	D95 H96 D210 H279
Binding residue (residue number reindexed from 1)	D94 H95 D209 H278
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.5.2.6: beta-lactamase.

Gene Ontology

	Molecular Function
GO:0008800	beta-lactamase activity
GO:0016787	hydrolase activity
GO:0042781	3'-tRNA processing endoribonuclease activity
GO:0046872	metal ion binding

	Biological Process
GO:0042780	tRNA 3'-end processing

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:7wi1, PDBe:7wi1, PDBj:7wi1
PDBsum	7wi1
PubMed	32664695
UniProt	A0A2U8UYM6

[Back to BioLiP]