Structure of PDB 7wh4 Chain B Binding Site BS01

Receptor Information
>7wh4 Chain B (length=101) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDPEFMREFQRAAVRLHILHHAADNEVHGAWLTQELSRHGYRVSPGTLYP
TLHRLEADGLLVSEQRVVDGRARRVYRATPAGRAALTEDRRALEELAREV
L
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7wh4 Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wh4 Crystal structure of PadR-family transcriptional regulator Rv3488 of Mycobacterium tuberculosis H37Rv in complex with Manganese ion
Resolution2.8 Å
Binding residue
(original residue number in PDB)		H16 E30 H34
Binding residue
(residue number reindexed from 1)		H21 E35 H39
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7wh4, PDBe:7wh4, PDBj:7wh4
PDBsum7wh4
PubMed
UniProtI6X7F9|CDDTR_MYCTU Transcriptional regulator Rv3488 (Gene Name=Rv3488)

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