Structure of PDB 7wh0 Chain B Binding Site BS01

Receptor Information
>7wh0 Chain B (length=529) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEAEGFPRLFHNFENVPEPKECKKVGSVPSYLTGTMLRNGPGMFTVGEEE
YKHWFDGLGFMQRYHFEDGKMFYSARYLESEAYTKTVEAQRIVAGTFGTL
SFPDPCKTIFSKYFSEFMNHSEKHDNSNVAFTPVGDSLYACTETPHMYRV
DLDTLKTLEAADFSKFVAVHSCTAHQLYDENGDVYNIGSRFGPESAHVFT
VTKNPKNQKSENDHSWEHTSKIGEIKASDPLYPTYMHSFGMSENYLVMFE
SPVRLHLQKYLLSEFVRATYHDCLEWHGDKDVSIFILNKKTGEQLPLTLK
MNPFFTFHHANTFEKDGCLVMDYCRIENAGKFDTLLISNMKTGEFQYDAK
FLPYLTRVIVPMSVSSSAKPGDNLLKSVPWASGCTSILQDDGSIRLTERR
VCETSMEFPRYHWEKINMKEYRYVFGSTVFGRIDGNLAGVVKADLKFGNH
LIWNRENPHQICGEPIFVPNPEGIEEDDGILIVPIMSSSEKQVPFVLILD
AKTLEETARFEIPEARIPLGFHAFYKPKN
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain7wh0 Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7wh0 Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans .
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H175 H237 H308 H522
Binding residue
(residue number reindexed from 1)		H175 H237 H308 H522
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003834 beta-carotene 15,15'-dioxygenase activity
GO:0010436 carotenoid dioxygenase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
Biological Process
GO:0016121 carotene catabolic process
GO:0042574 retinal metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7wh0, PDBe:7wh0, PDBj:7wh0
PDBsum7wh0
PubMed35223999
UniProtQ9U2E4

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