Structure of PDB 7vze Chain B Binding Site BS01
Receptor Information
>7vze Chain B (length=86) Species:
9606
(Homo sapiens) [
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NLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEG
DQVVLINGRDIAEHTHDQVVLFIKASCGELMLLVRP
Ligand information
>7vze Chain F (length=5) Species:
333760
(Human papillomavirus 16) [
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RETQL
Receptor-Ligand Complex Structure
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PDB
7vze
Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein.
Resolution
2.882 Å
Binding residue
(original residue number in PDB)
F528 G529 F530 N531 V532 Q538 S545 H579 D580 I586
Binding residue
(residue number reindexed from 1)
F15 G16 F17 N18 V19 Q25 S32 H66 D67 I73
Enzymatic activity
Enzyme Commision number
3.1.3.48
: protein-tyrosine-phosphatase.
External links
PDB
RCSB:7vze
,
PDBe:7vze
,
PDBj:7vze
PDBsum
7vze
PubMed
35089587
UniProt
P29074
|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)
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