Structure of PDB 7v38 Chain B Binding Site BS01

Receptor Information
>7v38 Chain B (length=207) Species: 11622 (Lassa virus Josiah) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIH
FFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQ
GSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGV
VVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRT
STPRVVL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7v38 Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7v38 Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites.
Resolution2.403 Å
Binding residue
(original residue number in PDB)		E399 C506 H509 C529
Binding residue
(residue number reindexed from 1)		E37 C144 H147 C167
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.13.-
External links
PDB RCSB:7v38, PDBe:7v38, PDBj:7v38
PDBsum7v38
PubMed34977900
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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