Structure of PDB 7us2 Chain B Binding Site BS01

Receptor Information

>7us2 Chain B (length=347) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SEAKYQEKQRKREAEERRRFPLEQRLKEHIIGQESAIATVGAAIRRKENG
WYDEEHPLVFLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQER
HEVAKFIGSPPGYVGHEEGGQLTKKLKQCPNAVVLFDQVDKAHPDVLTIM
LQLFDEGRLTDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMS
RNRIAETISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQ
LVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVER
RVVNQLAAAYEQDLLPGGCTLRITVEPKLRLEIIDKDSKTRRLDIRA

Ligand information

>7us2 Chain P (length=14) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

AAAAAAAAAAAAAA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7us2 PARL-cleaved Skd3 (human ClpB) E455Q Nucleotide Binding Domain hexamer bound to ATPgammaS, open conformation
Resolution	2.76 Å
Binding residue (original residue number in PDB)	G429 Y430 V431
Binding residue (residue number reindexed from 1)	G112 Y113 V114

Enzymatic activity

Enzyme Commision number

3.6.1.-

Gene Ontology

	Molecular Function
GO:0005524	ATP binding
GO:0016887	ATP hydrolysis activity

View graph for
Molecular Function

External links

PDB	RCSB:7us2, PDBe:7us2, PDBj:7us2
PDBsum	7us2
PubMed	37163603
UniProt	Q9H078\|CLPB_HUMAN Mitochondrial disaggregase (Gene Name=CLPB)

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