Structure of PDB 7uj1 Chain B Binding Site BS01

Receptor Information
>7uj1 Chain B (length=270) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGE
PGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAA
LSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKP
AARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQK
ERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESE
MEDAYHEHQANLLRQDLMRR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7uj1 Insight into the Tumor Suppression Mechanism from the Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) Complexed with a 30mer RNA from Murine Virus-like 30S Transcript-1.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		F300 N303 F327 K332 F334 F336 R360 Q361 R365 A367 T368 K466
Binding residue
(residue number reindexed from 1)		F28 N31 F55 K60 F62 F64 R88 Q89 R93 A95 T96 K194
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7uj1, PDBe:7uj1, PDBj:7uj1
PDBsum7uj1
PubMed35998361
UniProtP23246|SFPQ_HUMAN Splicing factor, proline- and glutamine-rich (Gene Name=SFPQ)

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