Structure of PDB 7ufu Chain B Binding Site BS01

Receptor Information
>7ufu Chain B (length=1038) Species: 216816 (Bifidobacterium longum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FLKPEQQLERCRRIVRQRVDPHIHPSIAQLTVESYDIPGEPMPSDEFFAK
LDRGDIDFKPFMLGSEWGTTWGTVWFRLTGTVPAGYPKGKPLELILDLGW
YPHSCGGHIEGLVYRADGTAIKAVHPLNYWVPFMDAEGNAQVPVAEDGSF
TLYLEAASNPLLLGVPPFIETELGDHATGKPDEPYVFKSADLAEFDERYE
NYSVDLDVVSSLMEFADKQSPRYWQLAKALQRSLNAYDERNPESVEAARA
VLAGVLAKPANASAMNVSAIGHAHIDSAWLWPVRETRRKVARTVSNALAL
MDADPDFKYAMSSAQQYAWLEEDHPDIFKRMKRRIEEGRFIPVGGMWVEA
DGMLPAGESLIRQIAYGRKYFKEHLGVEPKGVWLPASFGYTGAWPQIARR
AGYEWFLTQKISWNDTTKFPHHSFMWEGIDGSRIFTHFPPADTYAAWCKV
QELDYAEKNFQDKDLSDRSLLLFGFGDGGGGPTRNMMEHLHRYENLEGVS
KVSIEEPNDFFDKAHQQLAENAGPEMPVWKGELYLELHRGTLTSQQDMKR
GCRQEESLLRTVEYLGAAAVLSDPEYVYPREELDRIWKTLLLNQFHDILP
GSAIAWVHREAREDYRRDLKRLAEIAQDMCAVLRKANPQADLLAEARISQ
FRNDGASWHANRINEPTDALSVLTQTLDNGRVLLANGVLSVTIEADGTIS
SLLDEEHGRELVPAGTRLGQYELLRDEPAVWDAWEIERESLLMANAVTGS
IESVNTENGAAQVHVHTADGDTVITTTITLRPGSHTLDFHADIDWHERER
FLKVDLPLGIVADQATYDCQYGLIRRPIVKNTASDEAKYESSTNRFAIIG
DAGYAAAVINGSVYGSDASPIAGNAAEGRDSGTMFRLSLLSAPTFPDPRT
DIGSHEFDWSVVADATVDRALDAAGVLNAPVLHDVPDITPLASIESVNGT
VVLDWMKLADDGSGDLIVRAYEAAGGQADAMLHVCPALAGASVHETNVLE
GDDLAADLPVALQDGRQNAEGATLHFGPFQLATLRITR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7ufu Chain B Residue 1101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ufu Cryo-EM Structure of Bl_Man38A nucleophile mutant in complex with mannose at 2.7 A
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H275 D277 H597
Binding residue
(residue number reindexed from 1)		H274 D276 H596
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004559 alpha-mannosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006013 mannose metabolic process
GO:0009313 oligosaccharide catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7ufu, PDBe:7ufu, PDBj:7ufu
PDBsum7ufu
PubMed
UniProtQ8G4Q1

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