Structure of PDB 7u9k Chain B Binding Site BS01

Receptor Information
>7u9k Chain B (length=330) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENICIVFGGKSAEHEVSILTAQNVLNAIYHVDIIYITNDGDWRKQNNITA
EIKSTDELHLEISQLLQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGN
GVLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDK
LNYPVFVKPANLGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNAR
EIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPADLDEDV
QLTLRNMALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMY
PKLWENMGLSYPELITKLIELAKERHQDKQ
Ligand information
>7u9k Chain F (length=2) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AA
Receptor-Ligand Complex Structure
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PDB7u9k Staphylococcus aureus D-alanine-D-alanine ligase in complex with ATP, D-ala-D-ala, Mg2+ and K+
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E16 H96 S183 Y252 R291 G312 S317
Binding residue
(residue number reindexed from 1)		E13 H77 S164 Y233 R272 G293 S298
Enzymatic activity
Enzyme Commision number 6.3.2.4: D-alanine--D-alanine ligase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0008716 D-alanine-D-alanine ligase activity
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:7u9k, PDBe:7u9k, PDBj:7u9k
PDBsum7u9k
PubMed37948922
UniProtQ2FWH3|DDL_STAA8 D-alanine--D-alanine ligase (Gene Name=ddl)

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