Structure of PDB 7tts Chain B Binding Site BS01
Receptor Information
>7tts Chain B (length=440) Species:
9606
(Homo sapiens) [
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SNKDAALLEAARANNMQEVSRLLSEGADVNAKHRLGWTALMVAAINRNNS
VVQVLLAAGADPNLGSFKGCTALHYAVLADDYRTVKELLDGGANPLQRNE
MGHTPLDYAREGEVMKLLRTSEAKYQEKQRKREAEERRRFPLEQRLKEHI
IGQESAIATVGAAIRRKENGWYDEEHPLVFLFLGSSGIGKTELAKQTAKY
MHKDAKKGFIRLDMSEFQERHEVAKFIGSPPGYVGHEEGGQLTKKLKQCP
NAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNV
ASDEIAQHALQLRQEALETISKNFKENVIRPILKAHFRRDEFLGRINEIV
YFLPFCHSELIQLVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVH
YGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDS
Ligand information
>7tts Chain P (length=14) Species:
9913
(Bos taurus) [
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AAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB
7tts
Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
G429 Y430 V431
Binding residue
(residue number reindexed from 1)
G232 Y233 V234
Enzymatic activity
Enzyme Commision number
3.6.1.-
Gene Ontology
Molecular Function
GO:0005524
ATP binding
GO:0016887
ATP hydrolysis activity
View graph for
Molecular Function
External links
PDB
RCSB:7tts
,
PDBe:7tts
,
PDBj:7tts
PDBsum
7tts
PubMed
36170828
UniProt
Q9H078
|CLPB_HUMAN Mitochondrial disaggregase (Gene Name=CLPB)
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