Structure of PDB 7to8 Chain B Binding Site BS01
Receptor Information
>7to8 Chain B (length=116) Species:
9606
(Homo sapiens) [
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PGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPM
DMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEK
IFLQKVAQMPQEEVEL
Ligand information
>7to8 Chain C (length=13) Species:
32630
(synthetic construct) [
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QRSLKLLKHLYHG
Receptor-Ligand Complex Structure
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PDB
7to8
BRD3-BD1 in complex with RaPID linear peptide 2xAcK.1 (diAcK)
Resolution
1.5 Å
Binding residue
(original residue number in PDB)
W57 V63 K67 L68 N69 N116 T119 D120 D121 I122 M125
Binding residue
(residue number reindexed from 1)
W26 V32 K36 L37 N38 N85 T88 D89 D90 I91 M94
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7to8
,
PDBe:7to8
,
PDBj:7to8
PDBsum
7to8
PubMed
37992806
UniProt
Q15059
|BRD3_HUMAN Bromodomain-containing protein 3 (Gene Name=BRD3)
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