Structure of PDB 7tb1 Chain B Binding Site BS01
Receptor Information
>7tb1 Chain B (length=126) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQ
QHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLA
KEQRLNFGDDIPSALRIAKKKRWNSI
Ligand information
>7tb1 Chain C (length=10) Species:
32630
(synthetic construct) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
ACSSIWCPDG
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7tb1
Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1.
Resolution
1.785 Å
Binding residue
(original residue number in PDB)
N34 F37 Y49 V61 N65 L68 K95 F98 Q102 F131 D134 I135
Binding residue
(residue number reindexed from 1)
N10 F13 Y25 V37 N41 L44 K71 F74 Q78 F107 D110 I111
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:7tb1
,
PDBe:7tb1
,
PDBj:7tb1
PDBsum
7tb1
PubMed
35853179
UniProt
Q9UNE7
|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (Gene Name=STUB1)
[
Back to BioLiP
]
