Structure of PDB 7tad Chain B Binding Site BS01

Receptor Information
>7tad Chain B (length=348) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PDVSALQLLSNSFESVFDSPDDFYSDAKLVLSDGREVSFHRCVLSARSSF
FKSALAAAKKAVKLELKEIAKDYEVGFDSVVTVLAYVYSSRVRPPPKGVS
ECADENCCHVACRPAVDFMLEVLYLAFIFKIPELITLYQRHLLDVVDKVV
IEDTLVILKLANICGKACMKLLDRCKEIIVKSNVDMVSLEKSLPEELVKE
IIDRRKELGLEVPKVKKHVSNVHKALDSDDIELVKLLLKEDHTNLDDACA
LHFAVAYCNVKTATDLLKLDLADVNHRNPRGYTVLHVAAMRKEPQLILSL
LEKGASASEATLEGRTALMIAKQATMAVECNSLKGRLCVEILEQEDKR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7tad Chain B Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7tad Structural basis of NPR1 in activating plant immunity.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		C150 C155 H157 C160
Binding residue
(residue number reindexed from 1)		C102 C107 H109 C112
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003712 transcription coregulator activity
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:1901149 salicylic acid binding
Biological Process
GO:0001666 response to hypoxia
GO:0009408 response to heat
GO:0009611 response to wounding
GO:0009617 response to bacterium
GO:0009625 response to insect
GO:0009626 plant-type hypersensitive response
GO:0009627 systemic acquired resistance
GO:0009682 induced systemic resistance
GO:0009751 response to salicylic acid
GO:0009862 systemic acquired resistance, salicylic acid mediated signaling pathway
GO:0010112 regulation of systemic acquired resistance
GO:0016567 protein ubiquitination
GO:0031347 regulation of defense response
GO:0031348 negative regulation of defense response
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0045893 positive regulation of DNA-templated transcription
GO:0050832 defense response to fungus
GO:0080027 response to herbivore
GO:0106167 extracellular ATP signaling
GO:1900424 regulation of defense response to bacterium
GO:2000022 regulation of jasmonic acid mediated signaling pathway
GO:2000031 regulation of salicylic acid mediated signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016604 nuclear body
GO:0090575 RNA polymerase II transcription regulator complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7tad, PDBe:7tad, PDBj:7tad
PDBsum7tad
PubMed35545668
UniProtP93002|NPR1_ARATH Regulatory protein NPR1 (Gene Name=NPR1)

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