Structure of PDB 7t80 Chain B Binding Site BS01

Receptor Information
>7t80 Chain B (length=209) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDPVLLNLPMNVTISENSPVSSFVAHVLASDLLTFNITAGNRERAFFINA
TTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVSLADEN
DNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLL
GTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTA
HLFITILDD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7t80 Chain B Residue 2101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7t80 Crystal Structure of Mouse Cadherin-23 EC18-19
Resolution2.301 Å
Binding residue
(original residue number in PDB)		E1839 D1892 E1894 D1931
Binding residue
(residue number reindexed from 1)		E16 D62 E64 D101
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7t80, PDBe:7t80, PDBj:7t80
PDBsum7t80
PubMed
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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