Structure of PDB 7t7t Chain B Binding Site BS01
Receptor Information
>7t7t Chain B (length=432) Species:
55188
(Citrus unshiu) [
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GRDEMQMSEAKRAYRSAKEEGNRQEEARWANVIGDILKNRGEYVEALKWF
RIDYDLLPTCQSLGEVYLRLEHFKDALIYQKKHLELAKDASVEQQRACTQ
LGRTYYEMFDHYSIRNAKKYFKSAMKLAQTFLKEYIDAHNNIGMLQMELD
NLEEAKKLLIRGLEICNEEEVSEDDDGRSRLHHNLGNVYMELRMWDKSRE
HIEQDIIICKKIEHRQGEAKGYINLGELHYRVQKYDEAILCYQKALNLAQ
SMEDEDALASQIDQNIETVKKAIEVMDELKKEEQNLKKLTRNMIGTSQER
KSLLQQNASLDCLIEKSSMIFAWLKHCEYAKRKKRIASELCDKGKLSDSF
LVIGESYQKLRKFNKAIKWYTKSWEMYKSIEGQALAKVNMGNVLDSNGDW
ALDPSVQLSALENMHYSHMIRFDNIEEARRLQ
Ligand information
>7t7t Chain X (length=25) Species:
3702
(Arabidopsis thaliana) [
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TKQTARKQLATKAARKSAPATGGVK
Receptor-Ligand Complex Structure
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PDB
7t7t
The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.
Resolution
3.17 Å
Binding residue
(original residue number in PDB)
R29 N32 D36 Q72 S73 R109 Q113 R116 D166 M173 E177 R209 H212 N216 D234 K249 N253 E256 Y259 Q290 N294 T297 A301 M351 N424 N427 D430 Y467
Binding residue
(residue number reindexed from 1)
R28 N31 D35 Q61 S62 R96 Q100 R103 D137 M144 E148 R180 H183 N187 D205 K220 N224 E227 Y230 Q261 N265 T268 A272 M319 N389 N392 D395 Y416
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006325
chromatin organization
GO:0009933
meristem structural organization
GO:0040029
epigenetic regulation of gene expression
GO:0072423
response to DNA damage checkpoint signaling
Cellular Component
GO:0005634
nucleus
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:7t7t
,
PDBe:7t7t
,
PDBj:7t7t
PDBsum
7t7t
PubMed
35298257
UniProt
A0A2H5Q1B8
|TONSL_CITUN Protein TONSOKU (Gene Name=TSK)
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