Structure of PDB 7t7t Chain B Binding Site BS01

Receptor Information
>7t7t Chain B (length=432) Species: 55188 (Citrus unshiu) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRDEMQMSEAKRAYRSAKEEGNRQEEARWANVIGDILKNRGEYVEALKWF
RIDYDLLPTCQSLGEVYLRLEHFKDALIYQKKHLELAKDASVEQQRACTQ
LGRTYYEMFDHYSIRNAKKYFKSAMKLAQTFLKEYIDAHNNIGMLQMELD
NLEEAKKLLIRGLEICNEEEVSEDDDGRSRLHHNLGNVYMELRMWDKSRE
HIEQDIIICKKIEHRQGEAKGYINLGELHYRVQKYDEAILCYQKALNLAQ
SMEDEDALASQIDQNIETVKKAIEVMDELKKEEQNLKKLTRNMIGTSQER
KSLLQQNASLDCLIEKSSMIFAWLKHCEYAKRKKRIASELCDKGKLSDSF
LVIGESYQKLRKFNKAIKWYTKSWEMYKSIEGQALAKVNMGNVLDSNGDW
ALDPSVQLSALENMHYSHMIRFDNIEEARRLQ
Ligand information
>7t7t Chain X (length=25) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TKQTARKQLATKAARKSAPATGGVK
Receptor-Ligand Complex Structure
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PDB7t7t The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.
Resolution3.17 Å
Binding residue
(original residue number in PDB)
R29 N32 D36 Q72 S73 R109 Q113 R116 D166 M173 E177 R209 H212 N216 D234 K249 N253 E256 Y259 Q290 N294 T297 A301 M351 N424 N427 D430 Y467
Binding residue
(residue number reindexed from 1)
R28 N31 D35 Q61 S62 R96 Q100 R103 D137 M144 E148 R180 H183 N187 D205 K220 N224 E227 Y230 Q261 N265 T268 A272 M319 N389 N392 D395 Y416
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006325 chromatin organization
GO:0009933 meristem structural organization
GO:0040029 epigenetic regulation of gene expression
GO:0072423 response to DNA damage checkpoint signaling
Cellular Component
GO:0005634 nucleus

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Biological Process

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Cellular Component
External links
PDB RCSB:7t7t, PDBe:7t7t, PDBj:7t7t
PDBsum7t7t
PubMed35298257
UniProtA0A2H5Q1B8|TONSL_CITUN Protein TONSOKU (Gene Name=TSK)

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